The MTHFR enzyme adds a methyl element to folic acid for usability. Methylation processes also require this enzyme that is produced by the MTHFR gene. In the case of mutation of the gene, the body may not carry out detoxification effectively. MTHFR enzyme also helps the body respond to B vitamins which help in energy production.
People with MTHFR gene mutation should take methylated versions of B vitamins and methylfolate, the activated version of folate. Homocysteine Factors, a Pure Encapsulation product, has methylfolate, methylcobalamin (the active version of vitamin B12), and the active versions of vitamins B6 and B5. An additional ingredient is betaine, which helps in detoxification.
MTHFR gene mutation is a genetic predisposition. People with this mutation should keep their folate and vitamin B levels in check. They should invest in quality supplements.